What is uniprot-mcp?
uniprot-mcp is a MCP server by smaniches that query the UniProt knowledgebase (entries, features, variants, PTMs, GO terms, cross-references) with per-query SHA-256 provenance and offline replay. It is listed under Other and has 3 GitHub stars.
| Type | Mcp server |
|---|---|
| Author | smaniches |
| Repository | smaniches/uniprot-mcp |
| Popularity | 3 GitHub stars |
| Category | Other |
| Security | Low risk (84/100) |
| Rank | #2,479 of 4,418 MCP servers; #383 in Other |
| License | Apache-2.0 |
| Last commit | 2026-10-15 |
| Runs | Locally and in the cloud |
| Language | Python |
| Platforms | macOS, Windows, Linux |
Is uniprot-mcp safe to install?
uniprot-mcp scores 84/100 on the MCPMods security check: Low risk. Things to review: sends your data to a cloud service. It passed 4 of 6 checks.
MCP server results come from listing signals: who publishes it, where your data goes and what it can do. The code itself is not scanned yet.
| Check | Result |
|---|---|
| Community-built server | Note |
| Sends your data to a cloud service | Review |
| No credentials mentioned | Pass |
| Read-only by description | Pass |
| No code execution | Pass |
| Source on GitHub | Pass |
How do I install uniprot-mcp?
- Find the launch command. The README says how the server starts (npx, uvx, docker or a remote URL) and which API keys it needs.
https://github.com/smaniches/uniprot-mcp
- Add it to Claude Code. Replace the part after -- with the command from the README. Remote servers use --transport http with a URL.
claude mcp add uniprot-mcp -- <command from README> claude mcp add --transport http uniprot-mcp <server-url>
- Check it connected. This lists your MCP servers and their status.
claude mcp list
Or ask Claude to set it up
Paste this into Claude Code and it installs uniprot-mcp for you:
Add the "uniprot-mcp" MCP server from https://github.com/smaniches/uniprot-mcp to Claude Code. Read its README for the launch command and any API keys I need, run claude mcp add, then check that it connects.